Structure of PDB 5dxr Chain B Binding Site BS01

Receptor Information
>5dxr Chain B (length=236) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dxr Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.28 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 L379 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 V72 L75 D226 L227 E230
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dxr, PDBe:5dxr, PDBj:5dxr
PDBsum5dxr
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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