Structure of PDB 5dxp Chain B Binding Site BS01

Receptor Information
>5dxp Chain B (length=230) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5dxp Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.201 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L539 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 V71 L221 E224
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dxp, PDBe:5dxp, PDBj:5dxp
PDBsum5dxp
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

[Back to BioLiP]