Structure of PDB 5dxm Chain B Binding Site BS01

Receptor Information
>5dxm Chain B (length=237) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dxm Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.37 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 L75 D228 L229 E232
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dxm, PDBe:5dxm, PDBj:5dxm
PDBsum5dxm
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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