Structure of PDB 5dxe Chain B Binding Site BS01
Receptor Information
>5dxe Chain B (length=225) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
LSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKD
HIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGME
HLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5dxe Chain D (length=11) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
HKLLHRLLQDS
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5dxe
Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I46 L60 V64 E68 E219
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5dxe
,
PDBe:5dxe
,
PDBj:5dxe
PDBsum
5dxe
PubMed
26928945
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
[
Back to BioLiP
]