Structure of PDB 5dx3 Chain B Binding Site BS01
Receptor Information
>5dx3 Chain B (length=224) Species:
9606
(Homo sapiens) [
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LSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINWAKR
VPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRN
QGKMVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGYTFKDH
IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEH
LYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5dx3 Chain D (length=11) Species:
9606
(Homo sapiens) [
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HKKLHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5dx3
Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Resolution
2.0903 Å
Binding residue
(original residue number in PDB)
I358 K362 E380 L539 M543
Binding residue
(residue number reindexed from 1)
I45 K49 E67 L215 M219
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5dx3
,
PDBe:5dx3
,
PDBj:5dx3
PDBsum
5dx3
PubMed
26928945
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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