Structure of PDB 5dwe Chain B Binding Site BS01

Receptor Information
>5dwe Chain B (length=229) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
EKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dwe Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution1.92 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 V71 E75 D218 L219 E222
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dwe, PDBe:5dwe, PDBj:5dwe
PDBsum5dwe
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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