Structure of PDB 5doe Chain B Binding Site BS01

Receptor Information
>5doe Chain B (length=219) Species: 10360 (Human herpesvirus 5 strain AD169) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PELELKYLNMMKMAITGKESICLPFNFHSHRQHTCLDISPYGNEQVSRIA
CTSCEDNRILPTASDAMVAFINQTSNIMKNRNFYYGFCKSSELLKLSTNQ
PPIFQIYYLLHAANHDIVPFMHAEDGRLHMHVIFENPDVHIPCDCITQML
TAAREDYSVTLNIVRDHVVISVLCHAVSASSVKIDVTILQRKIDEMDIPN
DVSESFERYKELIQELCQS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5doe Chain B Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5doe Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		C106 R119 H211
Binding residue
(residue number reindexed from 1)		C35 R48 H140
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0046765 viral budding from nuclear membrane
GO:0046802 exit of virus from host cell nucleus by nuclear egress

View graph for
Biological Process
External links
PDB RCSB:5doe, PDBe:5doe, PDBj:5doe
PDBsum5doe
PubMed26511021
UniProtP16794|NEC1_HCMVA Nuclear egress protein 1 (Gene Name=NEC1)

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