Structure of PDB 5dah Chain B Binding Site BS01
Receptor Information
>5dah Chain B (length=181) Species:
9606
(Homo sapiens) [
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EMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCR
KCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVST
MEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVT
CAQFAGLLCEEEADNVQYCGYCKYHFSKLKK
Ligand information
>5dah Chain C (length=9) Species:
9606
(Homo sapiens) [
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LATKAARKS
Receptor-Ligand Complex Structure
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PDB
5dah
The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Resolution
2.611 Å
Binding residue
(original residue number in PDB)
A54 C55 L107 I109 P110 F114 V117 M120 E179 D186 N187 V188 Y190
Binding residue
(residue number reindexed from 1)
A35 C36 L88 I90 P91 F95 V98 M101 E160 D164 N165 V166 Y168
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5dah
,
PDBe:5dah
,
PDBj:5dah
PDBsum
5dah
PubMed
26439302
UniProt
P55197
|AF10_HUMAN Protein AF-10 (Gene Name=MLLT10)
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