Structure of PDB 5d5n Chain B Binding Site BS01

Receptor Information
>5d5n Chain B (length=222) Species: 10360 (Human herpesvirus 5 strain AD169) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTLHDLHDIFREHPELELKYLNMMKMAITGKESICLPFNFHSHRQHTCLD
ISPYGNEQVSRIACTSCEDLPTASDAMVAFINQTSNIMKNRNFYYGFCKS
SELLKLSTNQPPIFQIYYLLHAANHDIVPFMHAEDGRLHMHVIFENPDVH
IPCDCITQMLTAAREDYSVTLNIVRDHVVISVLCHAVIDVTILQRKIDEM
DIPNDVSESFERYKELIQELCQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5d5n Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5d5n Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Core Nuclear Egress Complex Provides Insight into a Unique Assembly Scaffold for Virus-Host Protein Interactions.
Resolution2.44 Å
Binding residue
(original residue number in PDB)		C106 C122 C125 H211
Binding residue
(residue number reindexed from 1)		C48 C64 C67 H150
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0046765 viral budding from nuclear membrane
GO:0046802 exit of virus from host cell nucleus by nuclear egress

View graph for
Biological Process
External links
PDB RCSB:5d5n, PDBe:5d5n, PDBj:5d5n
PDBsum5d5n
PubMed26432641
UniProtF5HFZ4|NEC1_HCMVM Nuclear egress protein 1 (Gene Name=NEC1)

[Back to BioLiP]