Structure of PDB 5cfd Chain B Binding Site BS01

Receptor Information
>5cfd Chain B (length=232) Species: 434309 (Saffold virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPFPVTVREHAGTFFSTTPDTTVPVYGNTISTPFDYMCGEFTDLLSLCKI
PTFLGNLDSNKKRIPYFSATNSTPATPLVTYQVTLSCSCMANSMLAAVAR
NFNQYRGSLNYLFVFTGSAMTKGKFLISYTPPGAGEPKTLDQAMQATYAI
WDLGLNSSYNFTVPFISPTHYRQTSYNTPTITSVDGWLTVWQLTPLTYPL
GVPNDSHILTLVSGGDDFTLRMPVTFTKYVPQ
Ligand information
>5cfd Chain D (length=24) Species: 434309 (Saffold virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GNEGVIINNYYSNQYQNSIDLSAN
Receptor-Ligand Complex Structure
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PDB5cfd Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
P19 D20 T21 P24 G27 N28 T29 I30 S31 P33 D35
Binding residue
(residue number reindexed from 1)
P19 D20 T21 P24 G27 N28 T29 I30 S31 P33 D35
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:5cfd, PDBe:5cfd, PDBj:5cfd
PDBsum5cfd
PubMed27279624
UniProtC0MHL9|POLG_SAFV Genome polyprotein

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