Structure of PDB 5cdw Chain B Binding Site BS01
Receptor Information
>5cdw Chain B (length=100) Species:
9606
(Homo sapiens) [
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EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGN
DVQHFKVLRDGAGKYFLGVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
Ligand information
>5cdw Chain D (length=5) Species:
9606
(Homo sapiens) [
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SYVNV
Receptor-Ligand Complex Structure
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PDB
5cdw
Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.
Resolution
2.602 Å
Binding residue
(original residue number in PDB)
R15 R34 S36 S44 H55 F56 K57 L68
Binding residue
(residue number reindexed from 1)
R14 R33 S35 S43 H54 F55 K56 L67
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5cdw
,
PDBe:5cdw
,
PDBj:5cdw
PDBsum
5cdw
PubMed
26645482
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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