Structure of PDB 5c6d Chain B Binding Site BS01
Receptor Information
>5c6d Chain B (length=313) Species:
9606
(Homo sapiens) [
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SAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSL
SQTMGFPQDQIRLWPMQARSNGTKRPAMLDGNKTMIELSDNENPWTIFLE
TVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKI
RDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDG
DIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTL
SNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGPGNPLRHNYEGTLRDLLQF
FKPQPKKLYYQQL
Ligand information
>5c6d Chain D (length=7) Species:
9606
(Homo sapiens) [
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GKGKWKR
Receptor-Ligand Complex Structure
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PDB
5c6d
An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
Resolution
2.292 Å
Binding residue
(original residue number in PDB)
Q626 A627 R628 S629 N630 D653 E736 E744 D758 E759 M761 D764
Binding residue
(residue number reindexed from 1)
Q67 A68 R69 S70 N71 D90 E173 E181 D195 E196 M198 D201
Enzymatic activity
Enzyme Commision number
3.4.19.12
: ubiquitinyl hydrolase 1.
External links
PDB
RCSB:5c6d
,
PDBe:5c6d
,
PDBj:5c6d
PDBsum
5c6d
PubMed
26299963
UniProt
Q93009
|UBP7_HUMAN Ubiquitin carboxyl-terminal hydrolase 7 (Gene Name=USP7)
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