Structure of PDB 5b5v Chain B Binding Site BS01

Receptor Information
>5b5v Chain B (length=183) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINM
LYGTITDFCTEESCPVMSAGPKYEYHWADCSAPKYIDYLMTWVQDQLDDE
TLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHL
NTSFKHFIFFVQEFNLIDRRELAPLQELIEKLT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5b5v Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5b5v Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Resolution2.193 Å
Binding residue
(original residue number in PDB)		C79 C84 H161 H166
Binding residue
(residue number reindexed from 1)		C59 C64 H132 H137
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019209 kinase activator activity
GO:0019900 kinase binding
GO:0046872 metal ion binding
Biological Process
GO:0031952 regulation of protein autophosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5b5v, PDBe:5b5v, PDBj:5b5v
PDBsum5b5v
PubMed27335147
UniProtQ8BPB0|MOB1B_MOUSE MOB kinase activator 1B (Gene Name=Mob1b)

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