Structure of PDB 5aox Chain B Binding Site BS01

Receptor Information
>5aox Chain B (length=86) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIFEPADNKCLLR
ATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLK
Ligand information
>5aox Chain C (length=87) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggccgggcgcgguggcucacgccuguaaucccagcacuuugggaggccga
ggcgggaggaucgcgaacacgcgagaccccgucucua
<<<<<<<<<.<<..((>>.>>>>>....<<<<.)).....>>>>>>>><<
<<<<<<.<..<<<<<....>>>>>..>>>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5aox Retrotransposition and Crystal Structure of an Alu Rnp in the Ribosome-Stalling Conformation.
Resolution2.04 Å
Binding residue
(original residue number in PDB)
G2 G24 S25 Y27 K31 Y33 R36 T37 K38 P39 R59 K64 K66
Binding residue
(residue number reindexed from 1)
G1 G23 S24 Y26 K30 Y32 R35 T36 K37 P38 R50 K55 K57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008312 7S RNA binding
GO:0030942 endoplasmic reticulum signal peptide binding
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005786 signal recognition particle, endoplasmic reticulum targeting
GO:0048500 signal recognition particle

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5aox, PDBe:5aox, PDBj:5aox
PDBsum5aox
PubMed26585389
UniProtP37108|SRP14_HUMAN Signal recognition particle 14 kDa protein (Gene Name=SRP14)

[Back to BioLiP]