Structure of PDB 5ah5 Chain B Binding Site BS01

Receptor Information
>5ah5 Chain B (length=771) Species: 311403 (Rhizobium rhizogenes K84) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYDHRSRDAFWQQKWDEKRIFDWDPSSPGKKFYVLEMFPYTSGHLHIGHV
RNYSMGDTLARMQIARGYSVLHPMGWDSFGLPAENAARKFGTHPAKFTQD
AIDSMKRSMMQLGFGYSWANELATCSPTYVLAQQKLFLDLYRKGLIYRDD
TYVYWDPVEQTVLAAEQVIDGKGWRSGAAVYKRRTPQWFVDIRSYADRLL
DDLESLEGWPTSVRNIQRNWIGRTEGAEVRFLVEASDLTINAFTTRLDTL
AGCTFIALAPEHTILDRASVKDYCESILVLSSEERSAGAKSGIFTGLMVV
NPLNQERVPLYVANYVMPDFGTGAVIGVPDERDADFGALTSSAAREILIA
HLSEKLEGQKSTQYRLQNWSISRQRYWGCPIPIIHCSECGTIPVAEEQLP
ILLPDHLISEGSGSPLSRDESWMKAKCPQCGGDAARDPDTMDTFVDSSWY
FLRYPSPSSPNPIDSSLCNKIAPADVYIGGIEHATLHLIYSRFITKVLHD
LGYIEFDEPFVELYNQGMVNDVHGRKQSKSLGNVTDPSVVVQEFGADAVR
CYLLFKTTYNAPINWEDSGPQAMRSYLERVCRLFTNNLDRLRSSSAIEIC
PDDCENEEDREIARQLQLAIGKVTADVERFHFNAAIAAIMSVTNLLYEKG
GKASPTVLAGSLRLLVRLLAPFAPHISEELWALSGCNSLVAAEPWPTINE
RLVQAENIVLPVQINGKLIRTMTIPVNLAEEDILSTVLALPEVRSRLSDR
DLKNYRYVPNRIINLVVGLEH
Ligand information
>5ah5 Chain D (length=81) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccgcauggugaaaucgguaaacacaucgcacuaaugcgccgccucugg
cuugccgguucaaguccggcugcgggcacca
<<<<<<<..<<<...........>>>..<<<<....>>>>..<<<...>>
>..<<<<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB5ah5 Structural Characterization of Antibiotic Self-Immunity tRNA Synthetase in Plant Tumour Biocontrol Agent.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		N216 N220 T245 T246 S295 A296 A298 Y324 V325 M326 F329 V334 R343 R411 F601 K602 T603 T604 R625 R628 R675 H677 N679 A680 A683 M686 N690 P757 L764 T767 R802 R807 I808 N810
Binding residue
(residue number reindexed from 1)		N215 N219 T244 T245 S286 A287 A289 Y315 V316 M317 F320 V325 R332 R365 F555 K556 T557 T558 R579 R582 R629 H631 N633 A634 A637 M640 N644 P711 L718 T721 R756 R761 I762 N764
Enzymatic activity
Catalytic site (original residue number in PDB) F39 H47 H50 D78 D157 E160 F490 H529 F539 K572 K575
Catalytic site (residue number reindexed from 1) F38 H46 H49 D77 D156 E159 F444 H483 F493 K526 K529
Enzyme Commision number 6.1.1.4: leucine--tRNA ligase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004823 leucine-tRNA ligase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006429 leucyl-tRNA aminoacylation
GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ah5, PDBe:5ah5, PDBj:5ah5
PDBsum5ah5
PubMed27713402
UniProtB9JQP8

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