Structure of PDB 5ah0 Chain B Binding Site BS01

Receptor Information

>5ah0 Chain B (length=387) Species: 1122947 (Pelosinus fermentans DSM 17108)

MNSYPIVLVHGFMGWGRNEVLGLKYWGGITDYEQELSSYGYTAYTATVGP
VSSNWDRACELYAYIKGGTVDYGHAHSTQKGHSRYGRTYPGLYPEWGNLT
TEGKVNKIHLVAHSMGGQTVRTLVQLLKEGSEEERNTTPSQLSSLFAGGK
SWVHSITTIASPHDGTTLADGINIFGDFAKNLVASLASFTGAGEKLIYDF
KLDQWGLNRKSGESLTDYTNRVFNSAIWNSTNDLANWDLSTDGARVLNQW
VKAQSDIYYFSYSTCATVPSILTSNELPHVIYMTPLLYPFGRFIGSYTRN
EQGRVIIDNSWKPNDGVVNTISQNGPKIWSSDKIVNYNGVPQIGKWNSMP
LLDTIDHMDACGIGTNALTLSWYKGLAEKLSQLTISN

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 5ah0 Chain B Residue 1403

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5ah0 Characterization of a Poly(Butylene Adipate-Co-Terephthalate)-Hydrolyzing Lipase from Pelosinus Fermentans.
• Resolution: 2.5 Å
• Binding residue (original residue number in PDB): D71 H91 H97 D248
• Binding residue (residue number reindexed from 1): D56 H76 H82 D233
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.1.1.3: triacylglycerol lipase.

Gene Ontology

Molecular Function

• GO:0004806 triacylglycerol lipase activity
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0016042 lipid catabolic process

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:5ah0, PDBe:5ah0, PDBj:5ah0
• PDBsum: 5ah0
• PubMed: 26490551
• UniProt: A0A0A0YMQ9