Structure of PDB 5aeb Chain B Binding Site BS01
Receptor Information
>5aeb Chain B (length=266) Species:
506514
(uncultured bacterium BLR12) [
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QKVKEPTVSNADWSKPYRPFRIAGNLYYIGTYDLACYLITTKQGNIIVNT
GLAASALQIKNNIKALGFKLTDTKILLTTQAHYDHLGAMAEIKKITGAKL
MADEGDATVMADGGSSDYAFGGHGSMFEPIIADRLLHDKDTIQLGDTKLV
MLHHPGHTKGSCSFLFDTKDEQRSYRILIANMPTIVIEKKFSEVSSYPGI
AKDYAYTLQAMKNLSFDIWVASHASQFSMHSKHKPGDGYNPKSFMDRKGY
DESLDKLQKEYEKHLN
Ligand information
Ligand ID
CO
InChI
InChI=1S/Co/q+2
InChIKey
XLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Co+2]
CACTVS 3.341
[Co++]
Formula
Co
Name
COBALT (II) ION
ChEMBL
DrugBank
DB14205
ZINC
PDB chain
5aeb Chain A Residue 1311 [
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Receptor-Ligand Complex Structure
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PDB
5aeb
Crystal structure and kinetic analysis of the class B3 di-zinc metallo-beta-lactamase LRA-12 from an Alaskan soil metagenome.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
E140 H175
Binding residue
(residue number reindexed from 1)
E104 H137
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
Q116 H118 D120 H121 H196 K228 H263
Catalytic site (residue number reindexed from 1)
Q80 H82 D84 H85 H157 K189 H223
Enzyme Commision number
3.5.2.6
: beta-lactamase.
Gene Ontology
Molecular Function
GO:0046872
metal ion binding
View graph for
Molecular Function
External links
PDB
RCSB:5aeb
,
PDBe:5aeb
,
PDBj:5aeb
PDBsum
5aeb
PubMed
28750094
UniProt
B5L5V5
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