Structure of PDB 5a50 Chain B Binding Site BS01

Receptor Information
>5a50 Chain B (length=165) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDDLLGLLRIRIKRGVNLAVRDISSSDPYVVVKMGSQKLKTRVINKDVNP
EWNEDLTLSVTDSNLTVLLTVYDHDMFSKDDKMGDAEFEIKPYIEALRMQ
LDGLPSGTIVTTVKPSRRNCLAEESRVTWVDGKLVQDLVLRLRHVECGEV
EAQLQWIDLPGSSGL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5a50 Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5a50 Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D51 D56 D102 H103 D104
Binding residue
(residue number reindexed from 1)		D22 D27 D73 H74 D75
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008289 lipid binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006952 defense response
GO:0009651 response to salt stress
GO:0009738 abscisic acid-activated signaling pathway
GO:0009789 positive regulation of abscisic acid-activated signaling pathway
GO:1900426 positive regulation of defense response to bacterium
GO:1901002 positive regulation of response to salt stress
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5a50, PDBe:5a50, PDBj:5a50
PDBsum5a50
PubMed26719420
UniProtQ9LVH4|CAR4_ARATH Protein C2-DOMAIN ABA-RELATED 4 (Gene Name=CAR4)

[Back to BioLiP]