Structure of PDB 4zxs Chain B Binding Site BS01

Receptor Information
>4zxs Chain B (length=242) Species: 10299 (Human alphaherpesvirus 1 strain 17) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LHERQRYRGLFAALAQTPSEEIAIVRSLSVPLVKTTPVSLPFCLDQTVAD
NCLTLSGMGYYLGIGGCCPACNAGDGAATSREALILAFVQQINTIFEHRA
FLASLVVLADRHNAPLQDLLAGILGQPELFFVHTILRGGGACDPRLLFYP
DPTYGGHMLYVIFPGTSAHLHYRLIDRMLTACPGYRFVAHVWQSTFVLVV
RRNAPTVSAADIYCKMRDISFDGGLMLEYQRLYATFDEFPPP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4zxs Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zxs Structural basis of membrane budding by the nuclear egress complex of herpesviruses.
Resolution2.772 Å
Binding residue
(original residue number in PDB)		C106 C122 C125 H225
Binding residue
(residue number reindexed from 1)		C52 C68 C71 H169
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0046765 viral budding from nuclear membrane
GO:0046802 exit of virus from host cell nucleus by nuclear egress

View graph for
Biological Process
External links
PDB RCSB:4zxs, PDBe:4zxs, PDBj:4zxs
PDBsum4zxs
PubMed26511020
UniProtP10215|NEC1_HHV11 Nuclear egress protein 1 (Gene Name=NEC1)

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