Structure of PDB 4zn9 Chain B Binding Site BS01
Receptor Information
>4zn9 Chain B (length=235) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAHRLHAPTS
Ligand information
>4zn9 Chain D (length=9) Species:
9606
(Homo sapiens) [
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HKILHRLLQ
Receptor-Ligand Complex Structure
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PDB
4zn9
Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands.
Resolution
2.215 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 D219 E223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4zn9
,
PDBe:4zn9
,
PDBj:4zn9
PDBsum
4zn9
PubMed
22517684
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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