Structure of PDB 4zd5 Chain B Binding Site BS01

Receptor Information
>4zd5 Chain B (length=185) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQN
AFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTC
FMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCR
KPGLAHPHEGKVYTMVAQPGHVREINSKLQVVDLR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4zd5 Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4zd5 Structure of the catalytic domain of Sst2 F403A mutant at 2.07 Angstoms resolution
Resolution2.07 Å
Binding residue
(original residue number in PDB)		H356 C397 H404 H406
Binding residue
(residue number reindexed from 1)		H108 C149 H156 H158
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.19.-
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0061578 K63-linked deubiquitinase activity
GO:0140492 metal-dependent deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination
GO:0070536 protein K63-linked deubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:4zd5, PDBe:4zd5, PDBj:4zd5
PDBsum4zd5
PubMed
UniProtQ9P371|SST2_SCHPO AMSH-like protease sst2 (Gene Name=sst2)

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