Structure of PDB 4z7o Chain B Binding Site BS01

Receptor Information

>4z7o Chain B (length=464) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPE
SIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSI
QVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIG
FGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTR
FNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDA
KTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQK
NINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIR
SKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAK
VRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGN
GTFECGVCRCGPGW

Ligand information

>4z7o Chain G (length=4) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

AGDV

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4z7o beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece.
Resolution	2.85 Å
Binding residue (original residue number in PDB)	S121 Y122 S123 N215 A218 E220
Binding residue (residue number reindexed from 1)	S119 Y120 S121 N213 A216 E218

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:4z7o, PDBe:4z7o, PDBj:4z7o
PDBsum	4z7o
PubMed	26631735
UniProt	P05106\|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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