Structure of PDB 4yfy Chain B Binding Site BS01

Receptor Information
>4yfy Chain B (length=241) Species: 126385 (Providencia alcalifaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKILVISDNYQLVSYIKNLYLSNEEWSKELFIDYSYSSINRNPQSLIEL
GMTEIDIKNKNLNELNDYHLIISAHCKQIFPAHIVNNKLCINIHPGLNPY
NRGWFPQVFSILNKKPIGATIHKMDSEVDHGEIYCQEEVSILSHETSIDI
YNKVIELEKKLIKNNLLKIINNELQPKLPSQEGNYNSIQDFNKLCKLNLE
DNGSLREHIDLLRALTHGDFKNAYFYDENNTKVFVKIELSL
Ligand information
Ligand ID0FX
InChIInChI=1S/C16H27N3O14P2/c1-6-4-19(16(24)18-14(6)23)10-3-8(20)9(31-10)5-29-34(25,26)33-35(27,28)32-15-13(22)12(21)11(17)7(2)30-15/h4,7-13,15,20-22H,3,5,17H2,1-2H3,(H,25,26)(H,27,28)(H,18,23,24)/t7-,8+,9-,10-,11-,12+,13-,15-/m1/s1
InChIKeyUIVJXHWSIFBBCY-LPGAPTBISA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6CC1C(C(C(C(O1)OP(=O)(O)OP(=O)(O)OCC2C(CC(O2)N3C=C(C(=O)NC3=O)C)O)O)O)N
CACTVS 3.370C[CH]1O[CH](O[P](O)(=O)O[P](O)(=O)OC[CH]2O[CH](C[CH]2O)N3C=C(C)C(=O)NC3=O)[CH](O)[CH](O)[CH]1N
OpenEye OEToolkits 1.7.6C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OP(=O)(O)OP(=O)(O)OC[C@@H]2[C@H](C[C@@H](O2)N3C=C(C(=O)NC3=O)C)O)O)O)N
CACTVS 3.370C[C@H]1O[C@H](O[P](O)(=O)O[P](O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N3C=C(C)C(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1N
ACDLabs 12.01O=C1C(=CN(C(=O)N1)C2OC(C(O)C2)COP(=O)(OP(=O)(OC3OC(C(N)C(O)C3O)C)O)O)C
FormulaC16 H27 N3 O14 P2
NamedTDP-4-amino-4,6-dideoxyglucose
ChEMBL
DrugBank
ZINCZINC000030725213
PDB chain4yfy Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4yfy Molecular structure of an N-formyltransferase from Providencia alcalifaciens O30.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		N10 H75 K77 W104 F105 Q107 Y151 H217 F220 N222
Binding residue
(residue number reindexed from 1)		N10 H75 K77 W104 F105 Q107 Y151 H217 F220 N222
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004479 methionyl-tRNA formyltransferase activity
Biological Process
GO:0006413 translational initiation
GO:0009058 biosynthetic process
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4yfy, PDBe:4yfy, PDBj:4yfy
PDBsum4yfy
PubMed25752909
UniProtM9P0Q2

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