Structure of PDB 4y0f Chain B Binding Site BS01

Receptor Information
>4y0f Chain B (length=77) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF
TEYETQVKVMSQRHMIDGRWCDCKLPN
Ligand information
Receptor-Ligand Complex Structure
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PDB4y0f Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Resolution2.648 Å
Binding residue
(original residue number in PDB)		I107 L111 W113 K136 F149 R171 P178 N179
Binding residue
(residue number reindexed from 1)		I5 L9 W11 K34 F47 R69 P76 N77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

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Molecular Function
External links
PDB RCSB:4y0f, PDBe:4y0f, PDBj:4y0f
PDBsum4y0f
PubMed26883171
UniProtQ13148|TADBP_HUMAN TAR DNA-binding protein 43 (Gene Name=TARDBP)

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