Structure of PDB 4xxd Chain B Binding Site BS01
Receptor Information
>4xxd Chain B (length=206) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
VQLVESGGGLVQPGGSLRLSCAASGFTFSRYSMSWVRQAPGKGLELVAQI
NSVGSSTYYPDTVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCASGDY
WGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSG
ALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKV
DKKVEP
Ligand information
>4xxd Chain C (length=11) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KLVFFAEDVGS
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4xxd
Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
Resolution
2.41 Å
Binding residue
(original residue number in PDB)
F27 Y32 S33 Q50 S94 G95 D96
Binding residue
(residue number reindexed from 1)
F26 Y31 S32 Q49 S97 G98 D99
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4xxd
,
PDBe:4xxd
,
PDBj:4xxd
PDBsum
4xxd
PubMed
25880481
UniProt
P01857
|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)
[
Back to BioLiP
]
