Structure of PDB 4xgx Chain B Binding Site BS01

Receptor Information

>4xgx Chain B (length=293) Species: 83333 (Escherichia coli K-12)

TEVTVLEGKTMGTFWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTNKK
DSALMRFNDSQSLSPWPVSEAMADIVTTSLRIGAKTDGAMDITVGPLVNL
WGFPVQIPSQEQIDAMKAKTGLQHLTVINQSHQQYLQKDLPDLYVDLSTV
GEGYAADHLARLMEQEGISRYLVSVGGALNSRGMNGEGLPWRVAIQKAVV
DINGHGISTSGSYRNHVIDPQTGRPIEHNLVSVTVIAPTALEADAWDTGL
MVLGPEKAKEVVRREGLAVYMITKEGDSFKTWMSPQFKSFLVS

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 4xgx Chain B Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4xgx Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
• Resolution: 1.9 Å
• Binding residue (original residue number in PDB): T166 D280 T284
• Binding residue (residue number reindexed from 1): T149 D244 T248
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.1.180: FAD:protein FMN transferase.

Gene Ontology

Molecular Function

• GO:0016651 oxidoreductase activity, acting on NAD(P)H
• GO:0016740 transferase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0017013 protein flavinylation

Cellular Component

• GO:0005886 plasma membrane
• GO:1990204 oxidoreductase complex

External links

• PDB: RCSB:4xgx, PDBe:4xgx, PDBj:4xgx
• PDBsum: 4xgx
• PubMed: 26626129
• UniProt: P0AB85|APBE_ECOLI FAD:protein FMN transferase (Gene Name=apbE)