Structure of PDB 4xai Chain B Binding Site BS01

Receptor Information
>4xai Chain B (length=565) Species: 7070,83334 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALKDAQTNAAAEFPSAICESAAQLIFMNVQWVRSIPAFTCL
PLSDQLLLLEESWLDLFVLGAAQFLPLMDFSVLVEACGVLQQEPHRRDAF
LKEVADFQETLKKISQFQLDAHEFACLRAIVLFKTSFEEKTTTESAKISV
IQDDAQMRLNKHVTTTYPKQPLRFGKILLLVSSTFRTISGRTIEDLFFKK
VIRDTPIVAIISNMY
Ligand information
>4xai Chain Q (length=18) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ADTPALRQLSEYARPHVA
Receptor-Ligand Complex Structure
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PDB4xai Structural basis for corepressor assembly by the orphan nuclear receptor TLX.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E1201 A1204 F1208 F1379 K1381 R1384 D1385 N1394
Binding residue
(residue number reindexed from 1)		E378 A381 F385 F548 K550 R553 D554 N563
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Biological Process
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Cellular Component
External links
PDB RCSB:4xai, PDBe:4xai, PDBj:4xai
PDBsum4xai
PubMed25691470
UniProtP0AEY0|MALE_ECO57 Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9NCL0

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