Structure of PDB 4wwu Chain B Binding Site BS01

Receptor Information
>4wwu Chain B (length=347) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDTISFLRGVLLKRYDPQTKLLNLGALHSDPELIQKGVQSKMFPAMMKLA
STEKSLIVESVNLADNQLKDISAISTLAQTFPNLKNLCLANNQIFRFRSL
EVWKNKFKDLRELLMTNNPITTDKLYRTEMLRLFPKLVVLDNVIVRDEQK
LQTVYSLPMKIQQFFFENDALGQSSTDFATNFLNLWDNNREQLLNLYSPQ
SQFSVSVDSTIPPSTVTDSDQTPAFGYYMSSSRNISKVSSEKSIQQRLSI
GQESINSIFKTLPKTKHHLQEQPNEYSMETISYPQINGFVITLHGFFEET
GKPELENNKLSKKSFDRTWVIVPMNNSVIIASDLLTVRAYSTGAWKT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4wwu Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4wwu Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface.
Resolution3.301 Å
Binding residue
(original residue number in PDB)		H128 D171
Binding residue
(residue number reindexed from 1)		H28 D65
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4wwu, PDBe:4wwu, PDBj:4wwu
PDBsum4wwu
PubMed25618852
UniProtQ99257|MEX67_YEAST mRNA export factor MEX67 (Gene Name=MEX67)

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