Structure of PDB 4wsi Chain B Binding Site BS01

Receptor Information
>4wsi Chain B (length=359) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEV
LEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSKETVIHVKAHFDYDPS
DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG
KEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS
AVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTS
IDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALP
KPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEP
QWVPSTWLR
Ligand information
>4wsi Chain Y (length=18) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PRLEMDNVLKPPPEERLI
Receptor-Ligand Complex Structure
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PDB4wsi Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		P266 L267 A269 T270 V271 R272 S281 R282 V314 F318 P365 C366 E368 R516 Y528 G549 F551 Y556 S576 R578
Binding residue
(residue number reindexed from 1)		P15 L16 A18 T19 V20 R21 S30 R31 V63 F67 P106 C107 E109 R207 Y219 G240 F242 Y247 S267 R269
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4wsi, PDBe:4wsi, PDBj:4wsi
PDBsum4wsi
PubMed25385611
UniProtQ8N3R9|PALS1_HUMAN Protein PALS1 (Gene Name=PALS1)

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