Structure of PDB 4wpi Chain B Binding Site BS01
Receptor Information
>4wpi Chain B (length=340) Species:
9606
(Homo sapiens) [
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QQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEE
KVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAA
DGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMY
DPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNL
TERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYH
RVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKS
QGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLK
Ligand information
>4wpi Chain C (length=10) Species:
10299
(Human alphaherpesvirus 1 strain 17) [
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GPRKCARKTR
Receptor-Ligand Complex Structure
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PDB
4wpi
Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7.
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
N630 D682 H683 D684 V685 I709 E759 L760 M761 D762 D764
Binding residue
(residue number reindexed from 1)
N93 D140 H141 D142 V143 I167 E217 L218 M219 D220 D222
Enzymatic activity
Enzyme Commision number
3.4.19.12
: ubiquitinyl hydrolase 1.
External links
PDB
RCSB:4wpi
,
PDBe:4wpi
,
PDBj:4wpi
PDBsum
4wpi
PubMed
26046769
UniProt
Q93009
|UBP7_HUMAN Ubiquitin carboxyl-terminal hydrolase 7 (Gene Name=USP7)
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