Structure of PDB 4um9 Chain B Binding Site BS01
Receptor Information
>4um9 Chain B (length=448) Species:
9606
(Homo sapiens) [
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GCALGGTCEDCLLIGPQCAWCRCDTPANLLAKGCQLNFIENPVSQVEILK
NKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLY
YLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFV
KTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANI
DTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIV
CPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVH
LYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGL
NLSFTAICNNGTLFQHQKKCSHMKVGDTASFSVTVNIPHCERRSRHIIIK
PVGLGDALELLVSPECNCDCQVNSSKCHNGNGSFQCGVCACHPGPRCE
Ligand information
>4um9 Chain E (length=10) Species:
9606
(Homo sapiens) [
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GRGDLGRLKK
Receptor-Ligand Complex Structure
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PDB
4um9
Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
S125 A126 C180 I183 Y185 A217 N218 I219 T221 E223
Binding residue
(residue number reindexed from 1)
S106 A107 C161 I164 Y166 A198 N199 I200 T202 E204
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4um9
,
PDBe:4um9
,
PDBj:4um9
PDBsum
4um9
PubMed
25383667
UniProt
P18564
|ITB6_HUMAN Integrin beta-6 (Gene Name=ITGB6)
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