Structure of PDB 4tuz Chain B Binding Site BS01

Receptor Information
>4tuz Chain B (length=244) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLA
QLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tuz A structural perspective on nuclear receptors as targets of environmental compounds.
Resolution1.9 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 L68 V72 D233 L234 E237
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4tuz, PDBe:4tuz, PDBj:4tuz
PDBsum4tuz
PubMed25500867
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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