Structure of PDB 4tk3 Chain B Binding Site BS01

Receptor Information
>4tk3 Chain B (length=406) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPF
PASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIP
CGADAVVQVEDTELIRETEELEVRILVQARPGQDIRPIGHDIKRGECVLA
KGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKI
RDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSG
GVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIF
ALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPE
YHRCILTWHHQEPLPWAQSTMSMRSANGLLMLPPKTEQYVELHKGEVVDV
MVIGRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4tk3 Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		M326 D327 F330 R653 I656 Y673 M711 P713 Y719 D729
Binding residue
(residue number reindexed from 1)		M8 D9 F12 R331 I334 Y351 M381 P383 Y389 D399
Enzymatic activity
Enzyme Commision number 2.10.1.1: molybdopterin molybdotransferase.
2.7.7.75: molybdopterin adenylyltransferase.
Gene Ontology
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0032324 molybdopterin cofactor biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:4tk3, PDBe:4tk3, PDBj:4tk3
PDBsum4tk3
PubMed25531214
UniProtQ03555|GEPH_RAT Gephyrin (Gene Name=Gphn)

[Back to BioLiP]