Structure of PDB 4rue Chain B Binding Site BS01

Receptor Information
>4rue Chain B (length=252) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHP
CVSDQELGLLIKEVADALGGGADPQSSHSAWDLGSAFFFSITIITTIGYG
NVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIF
LKWHVPPELVRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLEAIYFVI
VTLTTVGFGDYVAGADPRQDSPAYQPLVWFWILLGLAYFASVLTTIGNWL
RV
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain4rue Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4rue Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		T129 I130 G131 T238 V239 G240
Binding residue
(residue number reindexed from 1)		T96 I97 G98 T205 V206 G207
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4rue, PDBe:4rue, PDBj:4rue
PDBsum4rue
PubMed25500157
UniProtQ9NYG8|KCNK4_HUMAN Potassium channel subfamily K member 4 (Gene Name=KCNK4)

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