Structure of PDB 4ra0 Chain B Binding Site BS01

Receptor Information
>4ra0 Chain B (length=377) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPTRLVAEFDFRTFDP
EGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHGMWQ
TISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPFHE
KDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSFY
PGSGFAFYSLDYMTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVALV
DKQLVVLAVEHTALALMEIKVCDGQEHVVTVSLRDGEATLEVDGTRGQSE
VSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTLEV
NRRLLDLDEAAYKHSDITAHSCPPVEP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4ra0 Chain B Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ra0 An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		D329 E331 R440 D656
Binding residue
(residue number reindexed from 1)		D49 E51 R160 D358
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4ra0, PDBe:4ra0, PDBj:4ra0
PDBsum4ra0
PubMed25242553
UniProtQ14393|GAS6_HUMAN Growth arrest-specific protein 6 (Gene Name=GAS6)

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