Structure of PDB 4r8t Chain B Binding Site BS01

Receptor Information
>4r8t Chain B (length=141) Species: 11072 (Japanese encephalitis virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTTGVYRIMARGILGTYQAGVGVMYENVFHTLWHTTRGAAIMSGEGKLTP
YWGSVKEDRIAYGGPWRFDRKWNGTDDVQVIVVEPGKAAVNIQTKPGVFK
TPLGEVGAVSLDYPRGTSGSPILDSNGDIIGLYGNGVELGD
Ligand information
>4r8t Chain A (length=21) Species: 11076 (Japanese encephalitis virus strain Nakayama) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SEFDMWLERAADITWEMDAAI
Receptor-Ligand Complex Structure
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PDB4r8t Fast native-SAD phasing for routine macromolecular structure determination.
Resolution2.133 Å
Binding residue
(original residue number in PDB)		T20 G21 V22 Y23 R24 I25 M26 A27 R28 F46 I58 M59 Q96 I98 A106 N108 Q110 L140 D141 S142
Binding residue
(residue number reindexed from 1)		T3 G4 V5 Y6 R7 I8 M9 A10 R11 F29 I41 M42 Q79 I81 A89 N91 Q93 L123 D124 S125
Enzymatic activity
Enzyme Commision number 3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:4r8t, PDBe:4r8t, PDBj:4r8t
PDBsum4r8t
PubMed25506719
UniProtO90417

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