Structure of PDB 4r4n Chain B Binding Site BS01

Receptor Information
>4r4n Chain B (length=342) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WKDANTTLFCASDAKAYDTEVHNVWATHACVPTDPSPQELKMENVTEEFN
MWKNNMVEQMHTDIISLWDQSLKPCVQLTGGSALTQACPKVTFEPIPIHY
CAPAGYAILKCNDKEFNGTGLCKNVSTVQCTHGIRPVVSTQLLLNGSLAE
GKVMIRSENITNNVKNIIVQLNESVTINCTRPNNSGGDIRQAHCNVSGSQ
WNKTLHQVVEQLRKYWNNNTIIFNSSSGGDLEITTHSFNCGGEFFYCNTS
GLFNGTASIENGTITLPCRIKQIINMWQRVGQAIYAPPIQGVIRCVSNIT
GLILTRDGGGNSNENETFRPGGGDMRDNWRSELYKYKVVKIE
Ligand information
>4r4n Chain b (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGRCAPTYCACV
Receptor-Ligand Complex Structure
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PDB4r4n Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
Resolution3.56 Å
Binding residue
(original residue number in PDB)
V281 S365 G366 G367 D368 E370 I371 S375 F376 N425 M426 W427 V430 G473 M475
Binding residue
(residue number reindexed from 1)
V164 S227 G228 G229 D230 E232 I233 S237 F238 N275 M276 W277 V280 G323 M325
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4r4n, PDBe:4r4n, PDBj:4r4n
PDBsum4r4n
PubMed25165110
UniProtQ0ED04

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