Structure of PDB 4pp6 Chain B Binding Site BS01

Receptor Information
>4pp6 Chain B (length=230) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pp6 Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Resolution2.201 Å
Binding residue
(original residue number in PDB)
I358 K362 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I50 K54 E72 D220 L221 E224
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4pp6, PDBe:4pp6, PDBj:4pp6
PDBsum4pp6
PubMed24771768
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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