Structure of PDB 4p9u Chain B Binding Site BS01

Receptor Information
>4p9u Chain B (length=272) Species: 666 (Vibrio cholerae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSPAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRL
ARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAAR
TNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAE
KIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIF
NGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQY
GIASGHIWNQMKMTLPSNFTED
Ligand information
Receptor-Ligand Complex Structure
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PDB4p9u The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand.
Resolution3.208 Å
Binding residue
(original residue number in PDB)		A33 E34 R35 R45 R49 I63 H65 G66 K67 T69
Binding residue
(residue number reindexed from 1)		A28 E29 R30 R40 R44 I58 H60 G61 K62 T64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000062 fatty-acyl-CoA binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006631 fatty acid metabolic process
GO:0019217 regulation of fatty acid metabolic process
GO:0071072 negative regulation of phospholipid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4p9u, PDBe:4p9u, PDBj:4p9u
PDBsum4p9u
PubMed25607896
UniProtQ9KQU8|FADR_VIBCH Fatty acid metabolism regulator protein (Gene Name=fadR)

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