Structure of PDB 4op4 Chain B Binding Site BS01

Receptor Information
>4op4 Chain B (length=265) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDSPVLALAKELISRQSVTPADAGCQDLMIERLKALGFEIESMVFEDTTN
FWARRGTQSPLFVFAGHTDVVPAGPLSQWHTPPFEPTVIDGFLHGRGAAD
MKGSLACMIVAVERFIAEHPDHQGSIGFLITSDEEGPFINGTVRVVETLM
ARNELIDMCIVGEPSSTLAVGDVVKNGRRGGGFLTDTGELLAAVVAAVEE
VNHQAPALLTTGGTSDGRFIAQMGAQVVELGPVNATIHKVNECVRIADLE
KLTDMYQKTLNHLLG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4op4 Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4op4 The Dimerization Domain in DapE Enzymes Is required for Catalysis.
Resolution1.651 Å
Binding residue
(original residue number in PDB)		D101 E136 H239
Binding residue
(residue number reindexed from 1)		D100 E135 H238
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.1.18: succinyl-diaminopimelate desuccinylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:4op4, PDBe:4op4, PDBj:4op4
PDBsum4op4
PubMed24806882
UniProtQ9KQ52|DAPE_VIBCH Succinyl-diaminopimelate desuccinylase (Gene Name=dapE)

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