Structure of PDB 4oj8 Chain B Binding Site BS01

Receptor Information

>4oj8 Chain B (length=271) Species: 555 (Pectobacterium carotovorum subsp. carotovorum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SEIVKFNPVMASGFGAYIDHRDFLEAKTETIKNLLMRQGFVVVKNLDIDS
DTFRDIYSAYGTIVEYADEKIGVGFGYRDTLKLEGEKGKIVTGRGQLPFH
ADGGLLLSQVDQVFLYAAEIKNVKFRGATTVCDHALACQEMPAHLLRVLE
EETFEVRVLERGYYVDVSPDGWFKVPVFTDLGWVRKMLIYFPFDEGQPAS
WEPRIVGFTDHETQAFFQELGAFLKQPRYYYKHFWEDGDLLIMDNRRVIH
EREEFNDDDIVRRLYRGQTAD

Ligand information

InChI=1S/Fe/q+2

CWYNVVGOOAEACU-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Fe+2]
CACTVS 3.341	[Fe++]

Formula

Name

FE (II) ION

PDB chain

4oj8 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	4oj8 Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics.
Resolution	2.1 Å
Binding residue (original residue number in PDB)	H101 D103 H251
Binding residue (residue number reindexed from 1)	H100 D102 H250
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.14.20.3: (5R)-carbapenem-3-carboxylate synthase.

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051213	dioxygenase activity

	Biological Process
GO:0017000	antibiotic biosynthetic process

	Cellular Component
GO:0005737	cytoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:4oj8, PDBe:4oj8, PDBj:4oj8
PDBsum	4oj8
PubMed	24604200
UniProt	Q9XB59\|CARC_PECCC (5R)-carbapenem-3-carboxylate synthase (Gene Name=carC)

[Back to BioLiP]