Structure of PDB 4njq Chain B Binding Site BS01

Receptor Information

>4njq Chain B (length=410) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGG
RYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNG
FLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVI
PNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREH
GITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLN
AEGDENCILVCTDHEEVPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAH
GVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSE
VPVQSFVTRSDMTASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVL
GAFYASSELP

Ligand information

Ligand ID

InChI

InChI=1S/Co/q+2

InChIKey

XLJKHNWPARRRJB-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Co+2]
CACTVS 3.341	[Co++]

Formula

Name

COBALT (II) ION

PDB chain

4njq Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4njq Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa
Resolution	2.702 Å
Binding residue (original residue number in PDB)	H82 D236 D307
Binding residue (residue number reindexed from 1)	H82 D236 D297
Annotation score	3

Enzymatic activity

Enzyme Commision number

3.4.11.-

Gene Ontology

	Molecular Function
GO:0004177	aminopeptidase activity
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:4njq, PDBe:4njq, PDBj:4njq
PDBsum	4njq
PubMed	24704201
UniProt	Q9HYZ3\|APEB_PSEAE Probable M18 family aminopeptidase 2 (Gene Name=apeB)

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