Structure of PDB 4n76 Chain B Binding Site BS01 |
| >4n76 Chain B (length=667) Species: 274 (Thermus thermophilus)
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HLGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGRVYPLLAQVARRAG
GVTVRMGDGLASWSPPEVLVLEGTLARQTYAYRLYPKGRRPLDPKDPGER
SVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGAVLDLW
VSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRTWELLR
LEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVARKPIPHLTGLLVP
VLTLEDLSLALSLPWEERRRRTREIASWIGRRLGLGTPEAVRAQAYRLSI
PKLMGRRAVSKPADALRVGFYRAQETALALLRLDGAQGWPEFLRRALLRA
FGASGASLRLHTLHAHPSQGLAFREALRKAKEEGVQAVLVLTPPMAWEDR
NRLKALLLREGLPSQILNVPLREEERHRWENALLGLLAKAGLQVVALSGA
YPAELAVGFDAGGRESFRFGGAACAVGGDGGHLLWTLPEAQAGERIPQEV
VWDLLEETLWAFRRKAGRLPSRVLLLRDGRVPQDEFALALEALAREGIAY
DLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTFLLLTVHRDFRGTPRPLK
LVHEAGDTPLEALAHQIFHLTRLYPASGFAFPRLPAPLHLADRLVKEVGR
LGIRHLKEVDREKLFFV |
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| PDB | 4n76 Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. |
| Resolution | 2.89 Å |
Binding residue
(original residue number in PDB) | A170 Y171 R172 I173 R192 R194 L265 S280 L281 R286 P412 M413 W415 K422 Q433 I434 N436 H445 R446 N449 K457 R580 R611 T613 P614 R615 A644 P650 R651 H657 R661 V685 |
Binding residue
(residue number reindexed from 1) | A164 Y165 R166 I167 R186 R188 L252 S262 L263 R268 P394 M395 W397 K404 Q415 I416 N418 H427 R428 N431 K439 R562 R593 T595 P596 R597 A626 P632 R633 H639 R643 V667 |
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