Structure of PDB 4n41 Chain B Binding Site BS01 |
| >4n41 Chain B (length=667) Species: 274 (Thermus thermophilus)
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GKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVARRAG
GVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPKDPG
ERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGAVLD
LWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRTWEL
LRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPRKPI
PHLTGLLVPVLTLEDLHSLALSLPWEERRRRTREIASWIGRRLGLGTPEA
VRAQAYRLSIPKLMGRRAVSKPADALRVGFYRAQETALALLRLDGAQGWP
EFLRRALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEEGVQAVLV
LTPPMAWEDRNRLKALLLREGLPSQILNVPLREEERHRWENALLGLLAKA
GLQVVALSGAYPAELAVGFDAGGRESFRFGGAACAVHLLWTLPEAQAGER
IPQEVVWDLLEETLWAFRRKAGRLPSRVLLLRDGRVPQDEFALALEALAR
EGIAYDLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTFLLLTVHRDFRGT
PRPLKLVHEAGDTPLEALAHQIFHLTRLYPASGFAFPRLPAPLHLADRLV
KEVGRLGIVDREKLFFV |
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| PDB | 4n41 Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. |
| Resolution | 2.248 Å |
Binding residue
(original residue number in PDB) | A170 Y171 R172 I173 Y197 T201 L217 Y226 H227 R232 I254 P255 V264 L279 R286 P412 M413 W415 K422 Q433 I434 N436 R446 N449 K457 E483 R548 R580 R611 T613 P614 R615 A644 P650 R651 H657 R661 V685 |
Binding residue
(residue number reindexed from 1) | A166 Y167 R168 I169 Y193 T197 L213 Y222 H223 R228 I250 P251 V260 L271 R278 P404 M405 W407 K414 Q425 I426 N428 R438 N441 K449 E475 R535 R567 R598 T600 P601 R602 A631 P637 R638 H644 R648 V667 |
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