Structure of PDB 4mut Chain B Binding Site BS01

Receptor Information
>4mut Chain B (length=188) Species: 1353 (Enterococcus gallinarum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGL
EKDIRLVSGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAI
DVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGIS
YEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4mut Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4mut Structural basis for the evolution of vancomycin resistance D,D-peptidases.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		H95 D102 H156
Binding residue
(residue number reindexed from 1)		H94 D101 H155
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008233 peptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4mut, PDBe:4mut, PDBj:4mut
PDBsum4mut
PubMed24711382
UniProtQ9JN36

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