Structure of PDB 4mdd Chain B Binding Site BS01
Receptor Information
>4mdd Chain B (length=220) Species:
9606
(Homo sapiens) [
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TLVSALETIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKA
IPGFRNLHLDDQMTLLQYSWMYLMAFALGWRSYRQSSANLLCFAPDLIIN
EQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL
KSQALFDAIRMTYIKELGKAIVKREGNSSQNSQRFYQLTKLLDSMHEVVE
NLLNYCFQTFLNIKKLLFHQ
Ligand information
>4mdd Chain D (length=12) Species:
9606
(Homo sapiens) [
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GLEDIIRKALMG
Receptor-Ligand Complex Structure
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PDB
4mdd
Crystal Structure of the Glucocorticoid Receptor Bound to a Non-steroidal Antagonist Reveals Repositioning and Partial Disordering of Activation Function Helix 12
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
V575 K579 M593 Q597
Binding residue
(residue number reindexed from 1)
V45 K49 M63 Q67
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4mdd
,
PDBe:4mdd
,
PDBj:4mdd
PDBsum
4mdd
PubMed
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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