Structure of PDB 4m38 Chain B Binding Site BS01

Receptor Information
>4m38 Chain B (length=334) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLK
KHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRA
NNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVDV
RNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQD
TVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFDVV
AKESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDAS
NGPLPTPVVFTEGKNYNFECNFSGDRVILHMQLC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4m38 Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		M75 E172 F174 G175 T176 M177 G180 E181 F246 Q329 W330
Binding residue
(residue number reindexed from 1)		M35 E132 F134 G135 T136 M137 G140 E141 F206 Q289 W290
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0016274 protein-arginine N-methyltransferase activity
Biological Process
GO:0018216 peptidyl-arginine methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4m38, PDBe:4m38, PDBj:4m38
PDBsum4m38
PubMed24726341
UniProtQ582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 7 (Gene Name=PRMT7)

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