Structure of PDB 4lsy Chain B Binding Site BS01

Receptor Information
>4lsy Chain B (length=88) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILTLRKKEPLDPQFQDHALK
GKWKPFRECHIKPDVSLVYLVKDDELILLRLGSHSELF
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain4lsy Chain B Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4lsy Crystal structure of apo and copper bound HP0894 toxin from Helicobacter pylori 26695 and insight into mRNase activity
Resolution1.895 Å
Binding residue
(original residue number in PDB)		E58 H84
Binding residue
(residue number reindexed from 1)		E58 H84
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004521 RNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006402 mRNA catabolic process
GO:0006415 translational termination

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Molecular Function
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Biological Process
External links
PDB RCSB:4lsy, PDBe:4lsy, PDBj:4lsy
PDBsum4lsy
PubMed24060809
UniProtO25554

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