Structure of PDB 4ls9 Chain B Binding Site BS01

Receptor Information
>4ls9 Chain B (length=319) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GARVDARGAADLLTAASSVSVICHVYPDADTIGAGLALAQVLAASGKHVE
VSFATPAQLPESLQSLPGGHLLVAPEAMRRDADLVVTVDIPSINRLGALS
GLAGPGREVLVIDHHASNQLFGTANYIDPSADSTTMLVAELLDAWGKPID
EKVAHCLYAGLTTDTGSFRWATARAHRLAARLVELGVDNASISRTLLDTH
PFAWLPMLSRVLATARLLPDALDGRGFVYAVVPHDEWSEARPEEVESIVD
IVRTTQQAEVAAVFKEIEPMHWSVSMRAKSVNLASVASAFGGGGHPHAAG
YSATGSADDVVQALARALG
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4ls9 Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ls9 Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D51 D110 H135 D185
Binding residue
(residue number reindexed from 1)		D30 D89 H114 D164
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4ls9, PDBe:4ls9, PDBj:4ls9
PDBsum4ls9
PubMed24878921
UniProtA0QVM9

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