Structure of PDB 4lkx Chain B Binding Site BS01

Receptor Information
>4lkx Chain B (length=219) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DIVMTQTPLSLSVTPGQPASISCRSSQSIVHSNGNTYLEWYLQKPGQSPQ
LLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCFQGSHVP
PTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGEC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4lkx Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.
Resolution1.92 Å
Binding residue
(original residue number in PDB)
H27D N30 Y32 K50 G91 V94
Binding residue
(residue number reindexed from 1)
H31 N35 Y37 K55 G96 V99
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:4lkx, PDBe:4lkx, PDBj:4lkx
PDBsum4lkx
PubMed24457896
UniProtQ0KKI6

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