Structure of PDB 4lkx Chain B Binding Site BS01
Receptor Information
>4lkx Chain B (length=219) Species:
9606
(Homo sapiens) [
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DIVMTQTPLSLSVTPGQPASISCRSSQSIVHSNGNTYLEWYLQKPGQSPQ
LLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCFQGSHVP
PTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGEC
Ligand information
>4lkx Chain R (length=14) Species:
9606
(Homo sapiens) [
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LAGGSAQSQRAPDR
Receptor-Ligand Complex Structure
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PDB
4lkx
Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.
Resolution
1.92 Å
Binding residue
(original residue number in PDB)
H27D N30 Y32 K50 G91 V94
Binding residue
(residue number reindexed from 1)
H31 N35 Y37 K55 G96 V99
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Cellular Component
GO:0005576
extracellular region
View graph for
Cellular Component
External links
PDB
RCSB:4lkx
,
PDBe:4lkx
,
PDBj:4lkx
PDBsum
4lkx
PubMed
24457896
UniProt
Q0KKI6
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